Five NEW chapters on:

- Pharmacovigilance

- Gastrointestinal microbiome and drug response

- The blood-brain barrier

Cannabis

Antibodies, immune checkpoint inhibitors, CAR-T cells, and other biological agents

Expanded coverage of the use of genetic polymorphisms in designing appropriate therapies

Revised and expanded chapter on pharmacodynamics and the molecular mechanisms of drug action

600+ color illustrations

■Drug Fact Tables summarizing clinical pharmacology

Content Outline and Abbreviation List at the beginning of each chapter

■50 NEW figures on mechanism of drug actions