The Calcutta Chromosome by Amitav Ghosh is an award-winning novel that masterfully blends science fiction, history, mystery, and speculative fiction. Set across different timelines, the story revolves around the mysterious disappearance of a researcher investigating the life and work of Sir Ronald Ross, the Nobel Prize-winning scientist who discovered the transmission of malaria. As the narrative unfolds, it weaves together scientific inquiry, secret societies, folklore, and alternative histories, raising profound questions about knowledge, power, memory, identity, and the limits of scientific understanding. Richly imaginative and intellectually engaging, the novel is celebrated for its unique fusion of science and storytelling